Dr Randy Schekman Explains Secretion of Large Particles and miRNA at HKUST

Randy-Schekman

Nobel Laureate in Physiology or Medicine Dr Randy Schekman Explains Secretion of Large Particles and miRNA at HKUST 25th Anniversary Distinguished Speakers Series

Dr Schekman described a pathway that mediates secretion of specific microRNAs through exosomes. Exosomes are cell-derived vesicles and are implicated to play key roles in processes such as the creation of a pre-metastatic niche in the spread of tumor cells. Dr Schekman showed a biochemical approach to isolate a unique exosome species and identify specific microRNAs including miR-223 that are enriched in the isolated exsomes. Dr Schekman further described the underlying molecular mechanisms that regulate packaging of miR-223 into exosomes.

http://www.ust.hk/about-hkust/media-relations/press-releases/nobel-laureate-physiology-medicine-dr-randy-schekman-explains-secretion-large-particles-mirna-hkust-25th-anniversary-distinguished-speakers-series-2/

https://www.nobelprize.org/nobel_prizes/medicine/laureates/2013/schekman-facts.html

 

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