HKUST Researchers Find Phase Transition in Postsynaptic Densities


A research team led by Prof Mingjie Zhang at HKUST, has achieved a breakthrough that provides mechanistic insights into the causes that lead to various neuropsychiatric disorders such as autism, intellectual disorders and schizophrenia. Their studies of the SynGAP/PSD-95 complex formation unexpectedly found physical phase transition in synaptic signaling activity of neurons. The research findings were published in Cell on August 25, 2016.

Original Article: Phase Transition in Postsynaptic Densities Underlies Formation of Synaptic Complexes and Synaptic Plasticity. Source:


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