Incretins are a group of gastrointestinal hormones that cause an increase in the amount of insulin released from the beta cells of the islets of Langerhans after eating and they also inhibit glucagon release from the alpha cells of the Islets of Langerhans.
GIP, typical incretin like GLP-1, was isolated and sequenced from intestinal mucosa as “gastric inhibitory peptide” in 1970, and then it was renamed as “glucose-dependent insulinotropic peptide”. It has been reported that GIP receptor is expressed in cells such as beta cell of pancreas, adipocyte or osteoblastic cell, and it plays essential roles in reserving of ingested nutrients within the body in each cell, and the control of GIP signal can lead to improvement of metabolic syndrome. It is rapidly inactivated to GIP (3-42) from active form of GIP (1-42) by DPP-IV in blood.
ELISA kits for GIP
Human GIP, Active form Assay Kit
Human GIP, Total Assay Kit
Mouse GIP, Active form (high sensitivity) Assay Kit
Mouse GIP, Total (high sensitivity) Assay Kit
Mouse GIP, Active form Assay Kit
Mouse GIP, Total Assay Kit
Rat GIP, Active form (high sensitivity) Assay Kit
Rat GIP, Total (high sensitivity) Assay Kit
Rat GIP, Active form Assay Kit
Rat GIP, Total Assay Kit